Investigate for possible causes (medical history, medications, medic alert tag, recent trauma).
Perform Blood Glucose analysis if available. If hypoglycemic, administer oral glucose if patient can tolerate oral medication.
If the patient has respiratory depression and a history suggestive of possible opiate overdose, initiate BVM ventilation first, then administer intranasal naloxone. Wait 2 minutes before providing another dose of naloxone – ensure adequate BVM ventilation is being provided during this time.
Establish a saline lock or an IV with 0.9% NaCl.
Apply cardiac monitor. Obtain a 12-lead electrocardiograph (ECG).
If an IV cannot be established and an urgent need for vascular access exists, establish IO access.